EASED: Extended Alternatively Spliced EST Database
نویسندگان
چکیده
منابع مشابه
EASED: Extended Alternatively Spliced EST Database
We established a database of alternative splice forms (ASforms) for nine eukaryotic organisms. ASforms are defined by comparing high-scoring ESTs with mRNA sequences using BLAST, taking known exon-intron information (from the Ensembl database). Filtering programs compare the ends of each aligned sequence pair for deletions or insertions in the EST sequence, which indicate the existence of alter...
متن کاملASDB: database of alternatively spliced genes
A database of alternatively spliced genes (ASDB) has been constructed based on (i) the results of the analysis of Swiss-Prot entries containing products of these genes and (ii) clustering procedure joining proteins that could arise by alternative splicing of the same gene. ASDB incorporates information about alternatively spliced genes, their products and expression patterns. It can be searched...
متن کاملAlternatively Spliced Human Genes by Exon Skipping - a database
UNLABELLED Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. Exon skipping is the most commonly known alternative splicing mechanism. A comprehensive database of alternative splicing by exon skipping is made available for the human genome data. 1,229 human genes are identified to exhibit alternative splicing by exon ski...
متن کاملAlternatively Spliced Genes
2 Alternative pre-mRNA Splicing 17 2.1 Alternative Splicing and its Role in Regulating Gene Activities and Generating Genetic Diversity 17 2.1.1 Different Patterns of Alternative Splicing 17 2.1.2 Alternative Splicing and Genetic Diversity 18 2.2 Mechanisms Underlying Alternative Splicing Regulation 19 2.2.1 Splicing Signals and Splicing Regulatory Elements 20 2.2.2 Trans-acting Splicing Regula...
متن کاملEST alignments suggest that [secret number]% of Arabidopsis thaliana genes are alternatively spliced
Recent estimates of the frequency of alternative splicing in human genes, in conjunction with recent estimates of the number of genes in the human genome, have confirmed that alternative splicing plays a critical role in human genetic complexity. However, despite this recent interest in alternative splicing as a fundamental genetic mechanism, and despite numerous experimentally confirmed exampl...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2004
ISSN: 1362-4962
DOI: 10.1093/nar/gkh136